Xeno-Free Hydrogels for 3D Cell Culture

VitroGel® is a user-friendly xeno-free hydrogel for 3D cell culture and more.  Create advanced ECM in less than 20 minutes.

Xeno-Free Hydrogel

Room Temp Stable

Easy Cell Harvesting

Lot-to-Lot Consistency

High-Throughput Capable

Discover all the advantages

Application Notes - Research Highlights

HPGDS in Adipose‑Derived MSCs Can Speed Wound Healing in Type 2 Diabetes

Institutions:Peking Union Medical College, Beijing, China Team:Ouyang L., Qiu, D., Fu, X., Wu, A., Yang, P., Yang, Z., Wang, Q., Yan, L., and Xiao, R. Application:Wound Healing Disease Model:Type 2 Diabetes Hydrogel:VitroGel® RGD [...]

Knocking Down Doors to Find Cancer Therapies Using Anti-Kinase Strategies

Institutions:University of South China, The University of Miami, University of Southern Califormia, The Ohio State University, The Ohio State University Wexner Medical Center, and University of California Team:Cui, J., Dean, D., Hornicek, F.J., [...]

Shining a (near-infrared) Light to Find Cancer

Institutions:Shandong University and University of Jinan, China Team:Chen Y., Zhang X., Xiaoya L., Wu H., Zhang D., Zhu B., and Huang S. Application:HSC2 or CAL-27 cells in VitroGel xenografted into nude mice- identification [...]

Check the MAP(K): Cancer Driver Signals on Pathway to Change Lanes

Institutions:Universitätsmedizin Berlin, and the German Cancer Consortium Team:Uhlitz F., Bischoff, P., Peidli, S., et al. Application:Cancer Research Disease Model:Colorectal Cancer Viability Analysis:Cyto3D Live-Dead Assay Kit Mitogen-activated protein kinases divert the normal developmental path [...]

Going 3D to Fight Cancer

Institutions:Rutgers Team:Bhatt, R., Ravi, D., Evens, A.M., and Parekkadan, B. Application:Cancer Research Disease Model:Lymphoma Hydrogel:VitroGel® Hydrogel Matrix Cells propagated in a hydrogel 3D cell culture grow more slowly than they do in 2D [...]

Functionalizing Xeno-Free VitroINK® Bioinks to Promote Cell-Cell Interactions Between Human-Induced Pluripotent Stem Cell-Derived Testis Cells for In Vitro Spermatogenesis

Introduction The differentiation of sperm, termed spermatogenesis, is coordinated by somatic cells within the seminiferous tubules of the testis niche. Spermatogonial stem cells – the progenitor cells which give rise to sperm – [...]

Patient-Derived Xenograft Using Xeno-Free VitroGel System in Comparison to Animal-based Matrigel

Introduction Patient-derived xenografts are becoming state-of-the-art for studying tumor behavior and drug responsiveness in a salient environment1. A patient-derived xenograft (PDX) is obtained when a tumor sample is removed from a patient, implanted [...]

Comparing the Xeno-Free VitroGel to Animal-Based Matrigel for Xenograft Studies

Introduction A cell-derived xenograft (CDX) model is the gold standard for anti-cancer therapies. The response of xenografts obtained in immune-deficient animals in drug testing is comparable to that in clinical practice, which makes [...]

Xeno-free Organoid Generation Workflow for Stem Cell Spheroids Using VitroGel® STEM and VitroGel® ORGANOID Hydrogel System

Application Note TheWell Bioscience, North Brunswick, NJ 08902 Over the past decade, advances in stem cells and 3D cell culture technologies have reignited interest in organoid research. Organoids are derived from stem cells [...]

3D Bioprinting of an Implantable Xeno-free Vascularized Human Skin Graft

Institutions: Yale University School of Medicine and several other institutions Team: Baltazar T., Jiang B., Moncayo A., Merola J., Albanna M., Salzman W.M., and Pober, J.S. Application: Production of xeno-free bioink for 3D [...]

Inhibition of CDK7-dependent Transcriptional Addiction is a Potential Therapeutic Target in Synovial Sarcoma

Institutions: University of Miami, UCLA, USC, and the Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China Team: Li X., Dean D.C., Yuan J., Temple T.H., Trent J.C., Rosenberg A.E., [...]

Enamel Matrix Derivative Enhances the Odontoblastic Differentiation of Dental Pulp Stem Cells via Activating MAPK Signaling Pathways

Institutions: Chinese Medical University, Liaoning Provincial Key Laboratory of Oral Diseases, Shenyang, China Team: Zhang B., Xiao M., Cheng X., Yu B., Chen H., Yu Q., and Qiu, L. Application: Creating and injectable [...]

VitroGel® RGD Hydrogel Improves the Therapeutic Effect of Bone Marrow-Derived Mesenchymal Stem Cells on Phosgene-Induced Acute Lung Injury in Rats

TheWell Bioscience VitroGel® RGD and VitroGel® 3D speed up how fast joints can repair themselves Institutions: Fudan University, Shanghai, China Team: Ding J., Sun Y., He D., Shao Y., Liu F., Zhang L., [...]

VitroGel® RGD-derivatized Hydrogels Can Support Cartilage Wound Healing

TheWell Bioscience VitroGel® RGD and VitroGel® 3D speed up how fast joints can repair themselves Institutions: Laboratorio di Immunoreumatologia e Rigenerazione Tissutale, Bolonga, Italy Team: Manferdini C., Trucco D., Saleh Y., Gabusi E., [...]

Centrosome Positioning in Migrating Dictyostelium Cells

  Institution: Ludwig Maximillian University, Munich, Germany Team: Ishikawa-Ankerhold H., Kroll J., van den Heuvel., Renkawitz J., and Müller-Taubenberger A. Application: New insight into how cells move through the environment in an amoeba-like [...]

News & Events

End-of-Year Promotion 2022

Enjoy our 2022 year-end promotion and stock up on all your favorite 3D cell culture [...]

2022 – International Society for Stem Cell Research

TheWell Bioscience is excited for Hera BioLabs to be presenting at AALAS 2022. Dr. Fallon [...]

ISSCR 2022 – International Society for Stem Cell Research

TheWell Bioscience is excited to be exhibiting at ISSCR 2022 (International Society for Stem Cell [...]

Patient-Derived Tumoroids in 3D Xeno-Free Hydrogel with Automated Biomarker Detection

Abstract 3D cell models like organoid and patient-derived tumoroid are becoming increasingly important for personalized [...]

AACR 2022 – American Association for Cancer Research

TheWell Bioscience is excited to be exhibiting at AACR 2022 (American Association for Cancer Research) [...]

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