Xeno-Free Hydrogels for 3D Cell Culture Research

VitroGel® is a user-friendly xeno-free hydrogel for 3D cell culture.  Create advanced ECM in less than 20 minutes.

Xeno-Free Hydrogel

Room Temp Stable

Easy Cell Harvesting

Batch-to-Batch Consistency

High-Throughput Capable

Discover all the advantages

Application Notes - Research Highlights

New hPSCs Expansion Method – Direct from Liquid Nitrogen to 3D Culture Using a Xeno-free Hydrogel – VitroGel® STEM

Culturing and maintaining human pluripotent stem cells (hPSCs) directly from cryopreservation using the xeno-free, hydrogel-based VitroGel® STEM Application Note TheWell Bioscience, North Brunswick, NJ 08902 Introduction Due to the advent of stem cell [...]

Identification of a Novel Antitumor Small-Molecule Known as MKI-1 via Activation of PP2A in Breast Cancer

Institutions:Korea Institute of Radiological and Medical Sciences, Seoul, South Korea; Radiological and Medico-Oncological Sciences, University of Science and Technology, Daejeon, South Korea; Department of Integrative Biotechnology, Sungkyunkwan University, Suwon, South Korea; New Drug [...]

miR-340 Restoration Promotes Macrophage Phagocytosis and Antitumor Immunity via Regulation of CD47 Expression

Institutions: Tianjin Medical University, Tianjin, China; Guangdong Pharmaceutical University, Guangzhou, China; University of Texas Southwestern Medical Center, Dallas, Texas, USA. Team: Xi q., Zhang J., Yang G., Zhang L., Chen Y., Wang C., [...]

KLF7: Discovery of a Novel Therapeutic Target and Biomarker for High-Grade Serous Ovarian Cancer

Institution: Department of Life Sciences and Public Health, Catholic University of the Sacred Heart, Milan, Italy Team:De Donato M., Babini G., Mozzetti S., Buttarelli M., Ciucci A., Arduini G., De Rosa M. C., [...]

Mesenchymal Stromal Cell-Derived CXCL12 Affects Tumor Growth by Macrophage M1 to M2 Polarization

Institution: Department of Clinical Pathology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran Team:Babazadeh S., Nassiri S. M., Siavashi V., Sahlabadi M., Hajinasrollah M., and Zamani-Ahmadmahmudi Z. Application:Identification of a new role [...]

New Findings Elucidate BMP4 and Decellularized Pulp Extracellular Matrix Synergy to Accelerate Tissue Formation by Stem Cells

Institution: Stomatological Hospital of Chongqing Medical University, Chongqing Medical University. People’s Republic of China Team:Tan Q., Cao Y., Zheng X., Peng M., Huang E., and Wang J. Application:Identification of a novel synergistic relationship [...]

Advanced Skin Cell Models Using the VitroGel® System: 2D Coating and 3D Cell Culture with Human Dermal Fibroblasts

Application Note Bhavya Shah, John Huang TheWell Bioscience, North Brunswick, NJ 08902 Introduction Despite recent progression, the need for reliable, repeatable in vitro three-dimensional (3D) tissue culture human skin models exist to further [...]

Advanced 3D Luminal Breast Cancer Model in VitroGel® System: Long-term 3D Cell Culture and Co-culture with Fibroblast Cells

Application Note Nana-Fatima Haruna, Bhavya Shah,John HuangTheWell Bioscience, North Brunswick, NJ 08902 Introduction There is an increasing need for the generation of data that accurately reflects the biological systems of patients 1-3. To [...]

Targeting Soluble Vimentin to Suppress Metastatic Breast Cancer Models In Vivo and In Vitro

Institution: Precision Medicine Research Center, Seoul National University Team: Pang, K., Park, J., Ahn, S. G., Lee, J., Park, Y., Ooshima, A., Mizuno, S., Yamashita, S., Park, K.-S., Lee, S.-Y., Jeong, J., Ushijima, [...]

Comparison between 2D and 3D Cell Cultured Adipose-derived Mesenchymal Stem Cells

Institution: Cancer Center at the First Hospital of Jilin University Team: Qiliang Yin, Na Xu, Dongsheng Xu , Mingxin Dong, Xiumin Shi, Yan Wang, Zhuo Hao, Shuangshuang Zhu, Donghai Zhao, Haofan Jin, and [...]

ovarian cancer study
ATR and phospho-ATR ser428 (p-ATR) Expression in Ovarian Cancer Prognosis

Institution: The First Affiliated Hospital of Zhengzhou University David Geffen School of Medicine at UCLA Team: Wenlong Feng, Dylan C. Dean, Francis J. Hornicek, Jinglu Wang, Yanyan Jia, Zhenfeng Duan, and Huirong Shi [...]

VitroGel Hydrogel Used to Bridge the Gap Between In Vivo and In Vitro Pancreatic Islet Beta-cells Studies

Institution: Xiamen Medical College Team: Tianshu Lan, Jingyi Guo, Xiaoming Bai, Zengjiong Huang, Zhimin Wei, Guicheng Du, GuoliangYan, Lebin Weng, Xue Yi Application: Development of 3D islet pancreatic beta-cells (β-cells) Disease Model: The [...]

Inhibition of Scar Proliferation with In-situ Cross Bonding of VitroGel Hydrogel and Adipose-derived Stem Cells Conditioned Medium

Institution: Fujian Medical University Team: Chaoyu Zhang, Ting Wang, Li Zhang, Penghong Chen, Shijie Tang, Aizhen Chen, Ming Li, Guohao Peng, Hangqi Gao, Haiyan Weng, Haoruo Zhang, Shirong Li, Jinghua Chen, Liangwan Chen, [...]

Development of Hypoxic-Responsive Lipid Polymer Nanoparticle for Eradication of Residual Glioma Cells

Institution: Institute of Nervous System Diseases, Xuzhou Medical University, Xuzhou Team: Haoyue Xu, Yuhan Han, Gang Zhao, Long Zhang, Zongren Zhao, Zhen Wang, Liang Zhao, Lei Hua, Konduru Naveena, Jun Lu, Rutong Yu, [...]

Long Term 3D Tumor Spheroid Culture in VitroGel Hydrogel Matrix

Application Note Nana-Fatima Haruna, Bhavya Shah, John Huang TheWell Bioscience, North Brunswick, NJ 08902 Introduction Cancer is a very meticulous disease that involves heterogeneous solid tumors subjected to complex extracellular conditions. These conditions, [...]

News & Events

Standard for Measuring Cell Viability in Scaffolds

We are excited that our VitroGel®, a xeno-free hydrogel system, is part of the National [...]

GHP Healthcare & Pharmaceutical Awards – Most Innovative 3D Hydrogel System 2020

GHP Magazine has Announced the Winners of the 2020 Healthcare & Pharmaceutical Awards Excited to [...]

TheWell Bioscience is recognized in “8 Top 3D Bioprinting Startups in Biotech”

Proud to be recognized as one of the “8 Top 3D Bioprinting Startups in Biotech”. [...]

ARMI Member Spotlight

We are excited to be a part of the ARMI BioFabUSA program. We look forward [...]

TheWell Bioscience Launches A New Generation of Bioinks for 3D Bioprinting

North Brunswick, NJ., January 16, 2020 – TheWell Bioscience Inc, a biotech company focusing on [...]